There is rarely a need for hospitalization. If OHSS does not improve with outpatient care, the woman may be treated in the hospital with close monitoring. The doctor may order intravenous IV fluids and medicines for nausea and may remove fluid from the abdomen.
Other supportive therapy may be given as needed. Complications from OHSS can be severe. You may become dehydrated and pressure in your abdomen may increase from too much fluid. These problems can lead to blood clots forming within the blood vessels. Blood clots can travel to your lungs or to other important organs. This can be potentially life-threatening. These complications can usually be avoided by recognizing the signs, symptoms, and laboratory evidence that OHSS is getting worse and getting appropriate treatment.
OHSS symptoms usually appear a few days after ovulation. Symptoms usually resolve within two weeks, unless pregnancy occurs. Pregnant women often continue to have symptoms for weeks or more after a positive pregnancy test. The symptoms gradually go away, and the rest of the pregnancy is not affected. Even though embryos may appear normal, they can still fail to implant. There are many different reasons for this but it is believed that one common cause is that the embryo has an abnormal chromosome count.
IVF treatment can be stressful and intrusive and take a toll on mental and physical health of both partners. Some of the challenges are:. So now you know the worst. In the meantime our friendly staff and counselling services will do their best to support you through any difficult times. The friendly and professional team at Life Fertility Clinic are happy to answer any other questions you may have about the risks associated with treatment. Like most medical procedures and medications, fertility treatments and IVF do have some risks.
While we have highly skilled staff and use leading, clinically-proven techniques, this fact sheet outlines the possible rare complications and will help you understand the risks.
What to do? Weigh yourself daily and monitor changes. Refrain from intercourse until advised by the IVF nurse coordinator. Ensure you drink at least 2 litres of fluid daily including sports drinks such as Hydralyte.
Remain as active as is comfortable but avoid strenuous activity. Your doctor may request daily blood tests and an ultrasound. Measure your waist daily at the level of the belly button and monitor changes. Keep a measure of your fluid input and monitor your urine output. Ensure you drink at least 2 litres of fluid daily and more if you can tolerate it.
Drinks, such as Hydralyte, are good. Adnexal torsion Adnexal or ovarian torsion ovarian twisting is a condition where the stimulated ovary twists on itself cutting off its own blood supply. They include when: Your ovaries are not responding to hormone treatment. Your ovaries are over-responding to the hormones, risking hyperstimulation OHSS see above. Uterine abnormalities such as fibroids or polyps are unexpectedly detected on ultrasound.
Your own personal reasons. Multiple pregnancy risk Although the prospect of twins or triplets may seem attractive to some couples, multiple pregnancies are associated with increased risks of maternal and foetal complications. Maternal risks associated with multiple pregnancy: Miscarriage Haemorrhage Pregnancy induced high blood pressure Diabetes Anaemia Polyhydramnios excessive amounts of amniotic fluid surrounding the fetus Caesarean section Prolonged hospitalisation resulting in a higher risk of clots and infection.
Foetal complications associated with multiple pregnancy: Pre-term delivery — The average length of a pregnancy is 39 weeks for a single pregnancy, 35 weeks for twins and 33 for triplets. These babies are more likely to suffer serious, lifelong health problems, such as cerebral palsy and serious disability. The risk per pregnancy of producing a child with cerebral palsy is 8 times greater in twin pregnancies and 47 times greater in triplet pregnancies than in singleton pregnancies.
OHSS is a serious condition. Women may experience a broad spectrum of signs and symptoms ranging from mild, moderate to severe forms. When this condition develops, most women will experience enlarged ovaries see ultrasound image , mild forms with abdominal bloating, discomfort, shortness of breath and mild weight gain—this primarily water weight. However some women may develop a severe form of OHSS: it can cause massive fluid accumulation in the belly and around the lungs, heart and other areas.
Fluid accumulation may cause breathing and circulation problems. The kidneys can be compromised as well. OHSS occurs in patients who have a high response to ovulation induction medication and is especially acute for those patients who, with a high response to medication, then receive an HCG injection during ovulation induction or to trigger ovulation in preparation for egg retrieval.
It rapidly intensifies the moment pregnancy occurs when the placenta normally infuses the pregnancy hormone, HCG, into her circulation. It is therefore imperative to prevent OHSS by careful monitoring, using conservative administration of medications, and patient education. Fertility clinics should always have guidelines and treatment plans to prevent this serious disorder.
In rare cases, the OHSS occurs in spite of normal estradiol or normal follicular stimulation. In practically all cases of OHSS, the HCG trigger injection was given, which then prompts the body to respond by shifting water from our blood stream into our largest body cavities: the abdomen and chest spaces. We do our best to protect our patients from this life-threatening condition. Studies show that ten to fifteen percent of patients will develop mild to moderate hyper-stimulation syndrome going through IVF.
These patients will have mild to moderate abdominal pain, abdominal bloating or increased waist size, nausea, vomiting, diarrhea, tender ovaries, and mild weight gain.
These patients will have rapid weight gain, severe abdominal pain, persistent nausea and vomiting, blood clots in legs, decreased urination, shortness of breath and tight or enlarged abdomen.
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